Population
Rat glomerular mesangial cells and primary cultures of bovine glomerular endothelial cells
Comparison
Compounds releasing nitric oxide, including… vs Dibutyryl cGMP, pretreatment with genistein…
Design
Preclinical
Authors
Loading...
May implicate NO-SAPK signaling in glomerular apoptosis; leaves open relevance to human renal disease.
Nitric oxide activates stress-activated protein kinases in glomerular endothelial and mesangial cells, potentially playing a critical role in NO-induced apoptosis.
Pfeilschifter et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: