Population
Calcium release channel of sarcoplasmic reticulum (SR) from fast-twitch skeletal muscle
Design
Preclinical
Authors
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Provides first tetrameric architecture of skeletal RyR; leaves open functional and cardiac isoform implications.
This study provides detailed ultrastructural characterization of the ryanodine receptor/calcium release channel from skeletal muscle sarcoplasmic reticulum, revealing its fourfold symmetry and complex domain organization.
Saito et al. (1988) studied this question.
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