Why the study?
Does humoral immunity contribute to posttransplantation septal capillary injury syndrome in lung allografts, and does plasmapheresis improve these findings?
Population
22 lung transplant patients who developed posttransplantation septal capillary injury syndrome in the…
Comparison
Plasmapheresis vs Pretransplantation baseline values, and…
Design
Case_series
Authors
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Hypothesis-generating for plasmapheresis in lung allograft septal capillary injury; leaves open humoral immunity as rejection mechanism.
Does humoral immunity contribute to posttransplantation septal capillary injury syndrome in lung allografts, and does plasmapheresis improve these findings?
Humoral immunity to endothelial-based alloantigens may be a common mechanism of lung allograft rejection, presenting as septal capillary injury syndrome that responds to plasmapheresis.
Magro et al. (2002) studied this question.
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