Why the study?
Are higher circulating vitamin D concentrations associated with better left ventricular geometry and function in elderly individuals without overt cardiovascular disease?
Population
870 elderly participants without prior myocardial infarctions, heart failure, or prevalent valvular disease…
Comparison
Higher circulating serum 25-dihydroxyvitamin-D… vs Lower circulating serum 25-OH D concentrations
Design
Cohort
Follow-up
5 years
Authors
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Cross-sectional vitamin D associations with better LV function lack longitudinal support; leaves open causal effects in elderly without CVD.
Are higher circulating vitamin D concentrations associated with better left ventricular geometry and function in elderly individuals without overt cardiovascular disease?
Higher circulating vitamin D concentrations are cross-sectionally associated with better LV systolic function and smaller LV end-systolic diameter in the elderly, though not with longitudinal changes over 5 years.
Fall et al. (2012) studied this question.
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