January 1, 1993Acta Anaesthesiologica Scandinavica

Influence of high thoracic epidural anesthesia on left ventricular contractility assessed using the end‐systolic pressure‐length relationship

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Why the study?

Does high thoracic epidural anesthesia reduce left ventricular contractility in patients without cardiovascular disease?

Population

48 patients with ASA physical status 1 and 2 and without cardiovascular disease; 36 scheduled for elective…

Comparison

High thoracic epidural anesthesia with… vs Control without TEA or lumbar epidural…

Design

RCT, randomly assigned (for Groups 1, 2, and 3)

Authors

AGA. GoertzUniversity of Minnesota WSW. SeelingUniversidad Mayor HHH. HeinrichUniversity Hospital Münster

Discussion

Member takes

Implication

High thoracic epidural anesthesia reduces LV contractility even without pre-existing disease; confirms causal effect and warrants caution in anesthetic planning.

Structured PICO

Does high thoracic epidural anesthesia reduce left ventricular contractility in patients without cardiovascular disease?

Population

48 patients with ASA physical status 1 and 2 and without cardiovascular disease; 36 scheduled for elective upper abdominal surgery.

Intervention

High thoracic epidural anesthesia (TEA) with bupivacaine 0.25% (n=12) or bupivacaine 0.5% (n=12).

Comparator

Control without TEA (n=12) or lumbar epidural anesthesia (LEA) with bupivacaine 0.5% (n=10).

Outcome

Left ventricular contractility assessed using the end-systolic pressure-length relationship (left ventricular maximum elastance).surrogate

High thoracic epidural anesthesia significantly reduces left ventricular contractility, even in patients without pre-existing cardiac disease.

Cite This Study

Goertz et al. (1993) studied this question.

synapsesocial.com/papers/6a891c8a3aa2d8278f760be3 https://doi.org/10.1111/j.1399-6576.1993.tb03595.x

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Implication

High thoracic epidural anesthesia reduces LV contractility even without pre-existing disease; confirms causal effect and warrants caution in anesthetic planning.

Influence of high thoracic epidural anesthesia on left ventricular contractility assessed using the end‐systolic pressure‐length relationship

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Influence of high thoracic epidural anesthesia on left ventricular contractility assessed using the end‐systolic pressure‐length relationship

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider