Why the study?
What is the predictability of inspired isoflurane concentration during low-flow anaesthesia using a to-and-fro breathing system in adult patients requiring mechanical ventilation?
What is the predictability of inspired isoflurane concentration during low-flow anaesthesia using a to-and-fro breathing system in adult patients requiring mechanical ventilation?
During low-flow anesthesia with a to-and-fro system, inspired isoflurane concentration predictably reaches approximately 80% of the vaporizer setting after 5 minutes.
May support predictable isoflurane delivery in low-flow to-and-fro systems; leaves open prospective validation before wider use.
We have examined the predictability of inspired isoflurane concentration during low-flow anaesthesia using a to-and-fro breathing system. Twenty one adult patients requiring mechanical ventilation of the lungs during surgery took part in this study. Using a fresh gas flow of 2 l.min-1, the ratio of inspired isoflurane concentration to isoflurane vaporizer setting was found to be approximately 4/5th after 5 min of anaesthesia. The ratio was maintained throughout the procedure, except for a few minutes following each change in vaporizer setting.
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Gowrie‐Mohan et al. (1995) studied this question.
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