This study establishes a modified, reliable method for determining plasma renin activity in small samples.
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Enables PRA measurement in limited-volume samples; leaves open multicenter validation before routine use.
In order to establish a reliable method for the determination of plasma renin activity in small samples, we have compared the methods reported. The method of Boucher et al. was found to be reliable, and modified in the laboratory. Expression of renin activity by the first order reaction constant was emphasized.
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Imai et al. (1967) studied this question.
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