Key result
An improved method for measuring plasma renin activity achieved a 92% recovery rate and successfully differentiated normal subjects from those with renovascular hypertension and primary aldosteronism.
Population
79 human subjects including 30 normal controls, 21 with essential hypertension, 7 with renovascular…
Design
Other
Authors
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May aid PRA-based differentiation of hypertension subtypes; leaves open prospective validation before routine use.
This study describes a sensitive and practical method for measuring plasma renin activity, which can reliably distinguish between normal levels, elevated levels in renovascular hypertension, and suppressed levels in primary aldosteronism.
Yukio Miura (1969) studied Hypertension (n=79). Measurement of plasma renin activity using EDTA, DFP, and Dowex 50W-X4 chromatography was evaluated on Recovery rate of added synthetic angiotensin II. An improved method for measuring plasma renin activity achieved a 92% recovery rate and successfully differentiated normal subjects from those with renovascular hypertension and primary aldosteronism.
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