Why the study?
Are serum lipids and lipoproteins elevated in men after myocardial infarction compared to a representative population sample?
Are serum lipids and lipoproteins elevated in men after myocardial infarction compared to a representative population sample?
Post-MI patients, particularly younger men, have significantly higher rates of hyperlipoproteinemia, elevated cholesterol, and triglycerides compared to a random population sample.
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Lipid elevations associated with post-MI status, strongest in younger men; leaves open causal role and intervention effects.
A nonselected series of 229 postmyocardial infarction (MI) patients was studied for up to 2 years following hospitalization. Their lipoprotein patterns, serum cholesterol, and triglyceride values were compared to those of a random population sample of men at comparable ages. Hyperlipoproteinemia, cholesterol, and triglyceride elevations were more common in MI patients than in men in the random sample, occurring with greatest frequency in the younger patients. There was a trend toward higher mortality among patients with hyperlipoproteinemia. Types II A and B were very common in young patients. Serum cholesterol values were significantly higher in the youngest patients and serum triglycerides higher than in the controls in age groups ≦ 40, 46-50, and 51-55 years.
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Gustafson et al. (1972) studied this question.
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