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February 13, 1969New England Journal of Medicine

Impaired Orthostatic Tolerance after Bed Rest in Patients with Myocardial Infarction

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Why the study?

Does strict bed rest compared to modified bed rest impair orthostatic tolerance in patients convalescing from acute myocardial infarction?

Population

22 patients convalescing from acute myocardial infarction

Comparison

Strict bed rest for 9 to 24 days vs Modified bed rest

Design

Cohort

Follow-up

9 to 24 days

Authors

WAWalter H. AbelmannHeart Failure / Cardiomyopathy

Discussion

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Implication

Strict bed rest was associated with impaired orthostatic tolerance post-MI; leaves open optimal mobilization strategies in contemporary care.

Structured PICO

Does strict bed rest compared to modified bed rest impair orthostatic tolerance in patients convalescing from acute myocardial infarction?

P
Population
22 patients convalescing from acute myocardial infarction
I
Intervention
Strict bed rest for 9 to 24 days
C
Comparator
Modified bed rest
O
Outcome
Orthostatic tolerance (measurements of heart rate and blood pressure during 15 minutes of passive, upright tilt to 70° or passive sitting posture)surrogate

Strict bed rest after acute myocardial infarction leads to cardiovascular deconditioning and impaired orthostatic tolerance, highlighting the need for gradual and supervised mobilization.

Cite This Study

Walter H. Abelmann (1969) studied this question.

synapsesocial.com/papers/6a893a371fb56efa37d439eahttps://doi.org/10.1056/nejm196902132800702
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Circulatory changes associated with systemic hypotension in patients with acute myocardial infarction.1966 · 46 citations
  2. 2Hemodynamic Changes in Patients with Acute1965 · 54 citations
  3. 3Plasma Catechol Amine Concentrations in Myocardial Infarction and Angina Pectoris1959 · 207 citations
  4. 4The Urinary Output of Catechol Derivatives Including Adrenaline in Normal Individuals, in Essential Hypertension, and in Myocardial Infarction1953 · 47 citations
  5. 5Total Urinary Catechol Excretion in Cardiovascular and Other Clinical Conditions1954 · 41 citations