Why the study?
The stress produced by anesthesia and surgery may cause undesirable hemodynamic effects, and whether dexmedetomidine provides better hemodynamic control than midazolam as premedication required evaluation.
Does intravenous dexmedetomidine provide better hemodynamic control compared to midazolam when used as a premedication for patients undergoing anesthesia and surgery?
Does intravenous dexmedetomidine provide better hemodynamic control compared to midazolam when used as a premedication for patients undergoing anesthesia and surgery?
Dexmedetomidine may improve hemodynamic stability versus midazolam as premedication; extends RCT evidence for its selective use in at-risk patients.
The stress produced by anesthesia and surgery may produce undesirable hemodynamic effects. Different agents have been used as preoperative medication to eliminate or suppress stress reactions. We hypothesize Dexmedetomidine provides better hemodynamic control as compared to midazolam when used as a premedication for patients. In this study, we evaluated the effects of a pre-anesthetic single dose of intravenous Dexmedetomidine in a dose of 0.06 mcg/kg body weight with intravenous midazolam 0.05mg/kg body weight on hemodynamic parameters.
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Mridu Paban Nath (2024) studied this question.
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