Key result
Anti-tuberculosis therapy followed by radical pericardiectomy successfully resolved symptoms and ECG abnormalities in a 43-year-old immunocompromised patient with tuberculous pericarditis.
Case Report (n=1)
Timely diagnosis and a combination of anti-tuberculosis therapy and radical pericardiectomy can successfully treat tuberculous pericarditis in immunocompromised patients.
Should not yet change practice; hypothesis-generating for combined therapy in immunocompromised tuberculous pericarditis.
This case report details the presentation, diagnostic process, and management of tuberculous pericarditis (TBP) in a 43-year-old male with a history of chronic severe pericarditis, right-sided heart failure, and rheumatoid arthritis. The patient exhibited symptoms of chest pain and dyspnea and showed signs of ascites and mild lower limb edema. Our patient was found to have significant pericardial thickening and effusion, as well as necrotic lymph nodes. Diagnostic tests, including a positive QuantiFERON-TB test (QIAGEN, Hilden, Germany) and imaging studies, supported the diagnosis of TBP. Management involved a combination of anti-tuberculosis therapy and eventually, a radical pericardiectomy. This report underscores the importance of timely diagnosis and treatment in improving outcomes for patients with TBP.
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Alotaibi et al. (2024) conducted a case report in Tuberculous Pericarditis (n=1). Anti-tuberculosis therapy and radical pericardiectomy was evaluated on Symptom resolution and ECG improvement. Anti-tuberculosis therapy followed by radical pericardiectomy successfully resolved symptoms and ECG abnormalities in a 43-year-old immunocompromised patient with tuberculous pericarditis.
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