Key result
The highest quartile of visceral adipose index scores was associated with a significantly increased risk of developing hypertension compared to the lowest quartile (HR 1.526; 95% CI 1.194-1.952).
Why the study?
Hypertension is a major contributor to global disease burden and mortality, and the association between visceral adipose index and hypertension in Chinese adults required examination.
Does a higher Visceral Adipose Index increase the risk of incident hypertension in apparently healthy Chinese adults?
Cohort (n=8,374)
Yes
Does a higher Visceral Adipose Index increase the risk of incident hypertension in apparently healthy Chinese adults?
Hazard Ratio: 1.526 (95% CI 1.194–1.952)
p-value: p=< 0.01
Higher Visceral Adipose Index scores are significantly and longitudinally associated with the development of hypertension in apparently healthy Chinese adults.
VAI may refine hypertension risk stratification in Chinese adults; hypothesis-generating pending causal and interventional confirmation.
Hypertension is the most crucial single contributor to global burden of disease and mortality, while weight loss as a non-pharmacological strategy is recommended to reduce blood pressure. This study aims to examine the association between visceral adipose index (VAI) and hypertension in Chinese adults. Data were collected from the China Health and Nutrition Survey (CHNS), consisting of 8374 apparently healthy participants aged ≥18 years in the 2009 CHNS for cross-sectional analysis, and 4275 participants at entry from 2009 to 2011 for cohort analysis. Height, weight, waist circumference, blood pressure (BP), and blood lipid were measured. Information of population characteristics, smoking status, alcohol consumption, physical activity, and diet were determined by validated questionnaire. Higher VAI scores were significantly associated with higher BP levels and higher risk of hypertension after adjustment with potential confounders (all p-trend < 0.001). The adjusted hazard ratio of hypertension was 1.526 (95%CI: 1.194, 1.952; p-trend < 0.01) for participants in the highest quartile of VAI scores when compared with those in the lowest quartile after adjustment for age, physical activity, antihypertensive medication, total energy intake, salt intake, and other major lifestyle factors. VAI scores were significantly, longitudinally associated with hypertension development among apparently healthy Chinese adults.
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Xue et al. (2020) conducted a cohort in Hypertension (n=8,374). High visceral adipose index (VAI) scores vs. Lowest quartile of VAI scores was evaluated on Incidence of hypertension (HR 1.526, 95% CI 1.194-1.952, p=< 0.01). The highest quartile of visceral adipose index scores was associated with a significantly increased risk of developing hypertension compared to the lowest quartile (HR 1.526; 95% CI 1.194-1.952).
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