Population
15 FMD-susceptible Large White pigs, 8-10 weeks old
Design
Preclinical
Follow-up
up to 150 days
Authors
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Nasal neutralizing activity in pigs may guide mucosal FMD vaccine research; leaves open optimal regimens and translation beyond animal models.
Pigs develop neutralizing antibodies in both serum and nasal fluid following FMD infection or vaccination, though nasal fluid titers are not boosted by revaccination.
Francis et al. (1983) studied this question.
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