Key result
Non-enveloped enteric RNA viruses utilize both lytic and non-lytic mechanisms, including extracellular vesicles, to egress from infected cells.
Why the study?
Emerging evidence indicates some non-enveloped viruses exit cells without cell lysis or use both lytic and non-lytic mechanisms, and understanding viral egress may provide targets for antiviral therapies against enteric RNA viruses.
Population
Non-enveloped enteric RNA viruses from Picornaviridae, Reoviridae, Caliciviridae, Astroviridae, and Hepeviridae
Design
Review
Authors
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Egress pathways may yield antiviral targets; leaves open whether they can be therapeutically blocked in enteric RNA virus infections.
Understanding the lytic and non-lytic egress mechanisms of non-enveloped enteric RNA viruses may provide relevant targets for antiviral therapies.
Owusu et al. (2021) conducted a review in Non-enveloped enteric RNA virus infection. Viral egress mechanisms was evaluated. Non-enveloped enteric RNA viruses utilize both lytic and non-lytic mechanisms, including extracellular vesicles, to egress from infected cells.
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