Why the study?
Does starting dual antiplatelet therapy with aspirin and clopidogrel ≤ 24 h improve outcomes in patients with acute high-risk transient ischemic attack and minor ischemic stroke?
Does starting dual antiplatelet therapy with aspirin and clopidogrel ≤ 24 h improve outcomes in patients with acute high-risk transient ischemic attack and minor ischemic stroke?
This clinical practice guideline recommends starting dual antiplatelet therapy (aspirin and clopidogrel) within 24 hours for acute high-risk TIA and minor ischemic stroke.
Supports early DAPT adoption in high-risk TIA/minor stroke; extends RCT evidence into formal guidelines.
No takes yet. Share an insight, caveat, or question.
Ken Uchino (2019) studied this question. Dual antiplatelet therapy with aspirin and clopidogrel started within 24 hours is recommended for patients with acute high-risk transient ischemic attack or minor ischemic stroke.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: