Key result
Surgical treatment for prosthetic valve endocarditis after TAVI or Su-AVR in high-risk patients has a high but not prohibitive mortality rate, appearing favorable compared to conservative therapy.
Why the study?
The correct management and role of surgery for prosthetic valve endocarditis after TAVI or Su-AVR in high-risk patients remain a matter of debate.
Does surgical treatment improve outcomes compared to conservative medical therapy in high-risk patients with prosthetic valve endocarditis after TAVI or Su-AVR?
Does surgical treatment improve outcomes compared to conservative medical therapy in high-risk patients with prosthetic valve endocarditis after TAVI or Su-AVR?
Surgical intervention for prosthetic valve endocarditis post-TAVI or Su-AVR in high-risk patients may be a viable option despite high mortality, as conservative management has worse outcomes.
Transcatheter aortic valve implantation (TAVI) and sutureless aortic valve replacement (Su-AVR) enabled in the last years many patients at high or prohibitive risk to be treated for their severe symptomatic aortic valve stenosis. As often happens in medicine, new techniques bring not only new hopes, but also new problems. In recent years, alongside the lengthening of the life of these patients treated with TAVI or Su-AVR, cardiologists and cardiac surgeons have had to face the long-term complications associated with the implantation of these devices, such as the prosthetic infective endocarditis. The correct management of prosthesis valve endocarditis after TAVI or Su-AVR in high risk patients, and the possible role of surgery are a matter of debate because pushing the limits of the modern medicine and becoming a new challenge for cardiac surgeons of 21st century. In this review, we summarized the incidence, characteristics and evidences for this new and controversial problem of the cardiovascular community. Moreover, we investigated the outcomes reported in literature of the conservative and the surgical strategy. Although the reported mortality rate of surgical treatment is high, seems not prohibitive, mostly if compared to conservative medical therapy. The collaborative exchange between cardiologist, cardiac surgeons, clinical microbiologists and expert of imaging is mandatory to face this challenge.
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Pollari et al. (2020) conducted a review in Prosthetic infective endocarditis after TAVI or Su-AVR in high-risk patients. Surgical treatment (redo aortic valve replacement) vs. Conservative medical therapy was evaluated on Mortality. Surgical treatment for prosthetic valve endocarditis after TAVI or Su-AVR in high-risk patients has a high but not prohibitive mortality rate, appearing favorable compared to conservative therapy.
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