Why the study?
Does an IV test dose of lidocaine with epinephrine reliably increase heart rate or systolic blood pressure in adult patients anesthetized with isoflurane?
Population
30 adult patients anesthetized with 1% end-tidal isoflurane and nitrous oxide after endotracheal intubation
Comparison
3 mL of 1.5% lidocaine with epinephrine IV vs 3 mL of normal saline IV
Design
RCT, randomly assigned
Follow-up
4 minutes
Authors
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SBP >15 mm Hg criteria should supplant HR for test-dose detection under isoflurane; extends validation of SBP as the reliable marker in anesthetized adults.
Does an IV test dose of lidocaine with epinephrine reliably increase heart rate or systolic blood pressure in adult patients anesthetized with isoflurane?
Systolic blood pressure is a more reliable indicator than heart rate for detecting intravascular injection of an epinephrine-containing epidural test dose in adults under isoflurane anesthesia.
Tanaka et al. (1995) studied this question.
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