Key result
Nocturnal intermittent hypoxia, measured by integrated area of desaturation (IAD), was independently associated with left ventricular mass index in hypertensive men with sleep apnea (β = 0.262, P<0.05).
Why the study?
Is nocturnal intermittent hypoxia, defined by integrated area of desaturation (IAD), associated with left ventricular hypertrophy in middle-aged hypertensive men with obstructive sleep apnea?
Cross-Sectional (n=223)
Is nocturnal intermittent hypoxia, defined by integrated area of desaturation (IAD), associated with left ventricular hypertrophy in middle-aged hypertensive men with obstructive sleep apnea?
Effect estimate: β = 0.262
p-value: p=<0.05
Nocturnal intermittent hypoxia, measured by the integrated area of desaturation, is independently associated with left ventricular hypertrophy in middle-aged hypertensive men with obstructive sleep apnea.
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May inform hypoxia-focused risk stratification in hypertensive OSA; leaves open whether IAD modification alters LV remodeling.
Yamaguchi et al. (2015) conducted a cross-sectional in Hypertension and obstructive sleep apnea (n=223). Integrated area of desaturation (IAD) was evaluated on Left ventricular mass index (β = 0.262, p=<0.05). Nocturnal intermittent hypoxia, measured by integrated area of desaturation (IAD), was independently associated with left ventricular mass index in hypertensive men with sleep apnea (β = 0.262, P<0.05).
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