Why the study?
Does atrial pacing alter myocardial metabolism in patients with cyanotic congenital heart disease compared to controls?
Population
14 patients with cyanotic congenital heart disease and 7 noncyanotic controls (n=21)
Comparison
Atrial pacing (150-175/min) for 10 min vs Rest state and noncyanotic controls
Design
Cross-sectional
Follow-up
10 minutes
Authors
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Pacing may induce anaerobic myocardial metabolism in desaturating cyanotic CHD; hypothesis-generating for clinical impact and management.
Does atrial pacing alter myocardial metabolism in patients with cyanotic congenital heart disease compared to controls?
Myocardial metabolism is normal at rest in cyanotic congenital heart disease, but atrial pacing induces anaerobic metabolism in those who experience a drop in arterial oxygen saturation.
Friedli et al. (1977) studied this question.
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