Why the study?
Does myocardial oxidative metabolism differ between normal subjects and patients with cyanotic congenital heart disease during rest and stress?
Population
15 subjects: 8 normal subjects and 7 cyanotic patients
Comparison
Coronary sinus catheterization with stress testing vs Normal subjects
Design
Case-control
Authors
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Supports preserved myocardial metabolism in cyanotic CHD; hypothesis-generating for management and requires prospective validation.
Does myocardial oxidative metabolism differ between normal subjects and patients with cyanotic congenital heart disease during rest and stress?
Left ventricular myocardial oxidative metabolism remains intact in patients with cyanotic congenital heart disease despite hypoxemia, with adequate oxygen delivery during stress.
Scheuer et al. (2008) studied this question.
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