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December 1, 2014EuroInterventionOpen Access

Short-term clinical outcomes among patients undergoing transcatheter aortic valve implantation in Switzerland: the Swiss TAVI registry

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Key result

Transcatheter aortic valve implantation in an unselected Swiss cohort resulted in a 30-day all-cause mortality rate of 4.8%, with surgical access routes showing a higher mortality risk than transvascular routes.

Why the study?

What are the short-term clinical outcomes and safety profile of TAVI in an unselected, high-risk patient population in Switzerland?

Population

697 elderly patients undergoing TAVI for native aortic valve stenosis, degenerative aortic bioprosthesis, or…

Design

Cohort

Follow-up

30 days

Authors

PWPeter WenaweserInterventional / Structural CardiologySSStefan StorteckyInterventional CardiologyDHDik HegInterventional Cardiology

Discussion

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Implication

Supports preferring transvascular over surgical access in TAVI; leaves open confounding by indication in this observational cohort.

Study Design

Type

Cohort (n=697)

Multicenter

Yes

Structured PICO

What are the short-term clinical outcomes and safety profile of TAVI in an unselected, high-risk patient population in Switzerland?

P
Population
697 elderly patients (mean age 82.4 years, 51.5% female) with severe symptomatic aortic stenosis or regurgitation undergoing TAVI in Switzerland, followed for 30 days.
I
Intervention
Transcatheter aortic valve implantation (TAVI) using CE-mark approved devices via transfemoral (79.1%), transapical (18.1%), direct aortic (1.7%), or subclavian (1.1%) access.
O
Outcome
Short-term clinical outcomes at 30 days, including all-cause mortality, cerebrovascular events, and myocardial infarction.hard clinical

The Swiss TAVI registry demonstrates favorable 30-day clinical outcomes for TAVI in an unselected, high-risk elderly population, with low rates of early mortality and stroke.

Limitations

  • No information on the learning curve or the evolution of TAVI devices, procedures or outcomes over time
  • Clinical practice and expertise might be different in the participating centres
  • Potential underreporting of events and bias due to site-reported serious adverse events without on-site monitoring

Cite This Study

Wenaweser et al. (2014) conducted a cohort in Severe aortic stenosis or regurgitation (n=697). Transcatheter aortic valve implantation (TAVI) was evaluated on All-cause mortality at 30 days. Transcatheter aortic valve implantation in an unselected Swiss cohort resulted in a 30-day all-cause mortality rate of 4.8%, with surgical access routes showing a higher mortality risk than transvascular routes.

synapsesocial.com/papers/6a89a64e0f137e402b33586dhttps://doi.org/10.4244/eijv10i8a166

Topics

Transcatheter aortic valve replacementTAVR in low-risk patients
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Longitudinal Trends and Outcomes in Transcatheter Aortic Valve Implantation: a report from the SwissTAVI Registry.
  2. 2Longitudinal Trends and Outcomes in Transcatheter Aortic Valve Implantation: a report from the SwissTAVI Registry2026 · 1 citations
  3. 3Outcomes after Transcatheter Aortic Valve Implantation: a Single Center Registry of 350 Consecutive Cases2013 · 2 citations
  4. 4Early- and mid-term outcomes after transcatheter aortic valve implantation. Data from a single-center registry2016 · 19 citations
  5. 5The hospital results and 1-year outcomes of transcatheter aortic valve-in-valve procedures and transcatheter aortic valve implantations in the native valves: the results from the Swiss-TAVI Registry2018 · 42 citations