Key result
Diabetic children and healthy children with diabetic parents had significantly higher mean serum apoB levels compared to healthy children with nondiabetic parents (127 and 128 vs 90 mg/dL, P<0.05).
Case-Control (n=90)
p-value: p=< 0.05
Diabetic children and healthy children with diabetic parents have significantly higher apolipoprotein B levels compared to those with nondiabetic parents, indicating an early increased risk for dyslipidemia and atherosclerosis.
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May indicate early dyslipidemia risk in diabetic families; hypothesis-generating and should not yet change practice.
Hashemi et al. (2012) conducted a case-control in Type I diabetes mellitus or familial risk of diabetes (n=90). Type I diabetes or having diabetic parents vs. Healthy children with nondiabetic parents was evaluated on Serum levels of apoA1 and apoB (p=< 0.05). Diabetic children and healthy children with diabetic parents had significantly higher mean serum apoB levels compared to healthy children with nondiabetic parents (127 and 128 vs 90 mg/dL, P<0.05).
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