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September 1, 1957American Journal of Physiology-Legacy Content

A Possible Mechanism of Action of Quinidine

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Authors

WHWilliam C. HollandNational Oceanic and Atmospheric Administration

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Implication

Quinidine may suppress atrial excitability via reduced K efflux; leaves open clinical translation from isolated tissue.

Key Points

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Cite This Study

William C. Holland (1957) studied this question.

synapsesocial.com/papers/6a89af06273d243e4992e6efhttps://doi.org/10.1152/ajplegacy.1957.190.3.492
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE MODE OF ACTION OF QUINIDINE ON ISOLATED RABBIT ATRIA INTERPRETED FROM INTRACELLULAR POTENTIAL RECORDS1958 · 124 citations
  2. 2Quinidine-induced inhibition of transient outward current in cardiac muscle1987 · 160 citations
  3. 3Interactions of Quinidine and Potassium on Atrioventricular Transmission1967 · 47 citations
  4. 4Quinidine and Unidirectional Cation Fluxes in Atria1960 · 33 citations
  5. 5Effects of quinidine sulfate on the balance among active and passive cellular properties that comprise the electrophysiologic matrix and determine excitability in sheep Purkinje fibers.1987 · 15 citations