Key result
Acute ischemic stroke was associated with significantly reduced high-frequency heart rate variability compared to healthy controls, indicating impaired cardiac autonomic function across stroke subtypes.
Why the study?
Does acute ischemic stroke and its subtypes (LAA vs SVO) impair cardiac autonomic function as measured by heart rate variability compared to controls?
Observational (n=240)
No
Does acute ischemic stroke and its subtypes (LAA vs SVO) impair cardiac autonomic function as measured by heart rate variability compared to controls?
Absolute Event Rate: 2.98% vs 4.96%
p-value: p=0.0004
Acute ischemic stroke patients, regardless of LAA or SVO subtype, exhibit significant cardiac autonomic dysfunction as measured by reduced heart rate variability compared to controls.
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Supports autonomic monitoring in acute stroke; leaves open whether HRV predicts outcomes or guides subtype-specific therapy.
Chen et al. (2011) conducted an observational in Acute ischemic stroke (n=240). Acute ischemic stroke vs. Healthy controls was evaluated on High-frequency (HF) component of heart rate variability (ms^2) (p=0.0004). Acute ischemic stroke was associated with significantly reduced high-frequency heart rate variability compared to healthy controls, indicating impaired cardiac autonomic function across stroke subtypes.
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