Why the study?
Are circulating IL-18 levels elevated in patients with atrial fibrillation in the absence of structural heart disease?
Are circulating IL-18 levels elevated in patients with atrial fibrillation in the absence of structural heart disease?
Circulating IL-18 levels are significantly elevated in patients with atrial fibrillation, particularly persistent AF, suggesting a role in the inflammatory cascade of AF.
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IL-18 may mark inflammation in lone AF; leaves open causal role and need for prospective trials.
Luan et al. (2010) studied this question.
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