Why the study?
Does heparin and/or ECGS affect the release of haemostatic metabolites in human umbilical vein endothelial cells?
Population
Human umbilical vein endothelial cells (HUVEC)
Comparison
Heparin, crude endothelial cell growth factor… vs Basal conditions (absence of heparin or ECGS)
Design
Preclinical
Authors
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These cell-culture results require in vivo validation; leaves open any clinical effect of heparin or ECGS on haemostasis.
Does heparin and/or ECGS affect the release of haemostatic metabolites in human umbilical vein endothelial cells?
Heparin and endothelial cell growth supplement independently and synergistically modulate the release of haemostatic factors from human vascular endothelial cells.
Minter et al. (1992) studied this question.
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