July 1, 1998Echocardiography
Left Ventricular Diastolic Function in a Population Sample of Elderly Men
Why the study?
Do Doppler-derived indices of LV diastolic function distinguish between apparently healthy elderly men and those with cardiovascular disease?
Population
584 men aged 70 years from a health screening survey, including an apparently healthy subgroup and subjects…
Comparison
Echocardiography with Doppler to assess left… vs Comparison between apparently healthy subjects…
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
E/A should not guide diastolic assessment in elderly men; leaves open whether IVRT improves distinction from age-related changes.
Structured PICO
Do Doppler-derived indices of LV diastolic function distinguish between apparently healthy elderly men and those with cardiovascular disease?
P
Population
584 men aged 70 years from a health screening survey, including an apparently healthy subgroup (n=195) and subjects with coronary heart disease (CHD), hypertension, diabetes mellitus, and systolic dysfunction (ejection fraction < 40%).
I
Intervention
Echocardiography with Doppler to assess left ventricular (LV) diastolic function indices (E/A ratio, isovolumic relaxation time [IVRT], deceleration time [DT], and pulmonary venous blood flow).
C
Comparator
Comparison between apparently healthy subjects and those with cardiovascular diseases (CHD, hypertension, diabetes mellitus, systolic dysfunction).
O
Outcome
Doppler-derived indices of LV diastolic function and their ability to distinguish between apparently healthy subjects and those with cardiovascular diseases.surrogate
In elderly men, age-associated changes in LV compliance override the impact of cardiovascular diseases on the E/A ratio, making IVRT a more sensitive, albeit limited, index of diastolic dysfunction.
Cite This Study
Andrén et al. (1998) studied this question.