Why the study?
Controversies persist regarding which criteria define real remission in rheumatoid arthritis, when they should be used, and whether clinical remission equates to ultrasound remission.
A comprehensive definition of rheumatoid arthritis remission should ideally incorporate clinical, serological, and ultrasonographic parameters to prevent structural damage.
Ultrasound may refine RA remission definitions; leaves open whether integration prevents progression in prospective trials.
The prognosis of patients with rheumatoid arthritis (RA) has improved substantially in the last two decades due to the appearance of biological therapies, but above all, due to the improvement in the strategy and management of the disease. Our goal in RA should be to achieve remission, or in its absence, the lowest inflammatory activity. Achieving remission will prevent from structural and functional damage highly associated with RA itself. Clinical remission is defined as the absence of significant signs and symptoms of inflammatory disease activity, as well as the abrogation of any signs of systemic inflammation. Currently, there are some controversies about remission. Which is the real remission? Which remission criteria should be used and when? Does clinical remission mean ultrasound remission? In the present review, we try to answer and put some light into it, focusing on clinical and ultrasound deep remission.
No takes yet. Share an insight, caveat, or question.
Millán et al. (2020) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: