Population
Seven functionally different canine cardiac tissues
Comparison
[3H]-ouabain and Rb+ vs Comparison between specialized cardiac tissues…
Design
Preclinical
Authors
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Challenges accumulation hypothesis for Purkinje sensitivity in animals; leaves open alternative mechanisms and human translation.
The study demonstrates that the well-known sensitivity of Purkinje fibres to ouabain is not due to a higher accumulation of the drug in these tissues.
H. M. Rhee (1981) studied this question.
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