Why the study?
Does plasma glucagon mediate the stress response and hyperglycemia following abdominal surgery?
Population
42 patients undergoing abdominal surgery
Comparison
Abdominal surgery and arginine infusion vs Preoperative baseline
Design
Cohort
Follow-up
24 hours postoperatively
Authors
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Postoperative glucagon rise without hyperglycemia correlation suggests limited mediator role; hypothesis-generating for alternative surgical stress mechanisms.
Does plasma glucagon mediate the stress response and hyperglycemia following abdominal surgery?
Glucagon does not appear to be a primary mediator of the stress response or hyperglycemia following abdominal surgery.
Giddings et al. (1976) studied this question.
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