Why the study?
Does MK 950 reduce heart rate compared to propranolol in volunteers?
Population
6 volunteers
Comparison
MK 950 (oral doses, e.g., 2.5 mg, 5 mg) vs Propranolol (oral doses, e.g., 20 mg)
Design
Other
Authors
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May indicate high potency for MK 950; leaves open its comparative efficacy, safety, and outcomes versus propranolol in patients.
Does MK 950 reduce heart rate compared to propranolol in volunteers?
MK 950 is a potent beta-adrenergic blocker that achieves equivalent heart rate reduction at substantially lower doses than propranolol.
Ulrych et al. (1972) studied this question.
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