Why the study?
Are cardiovascular and neuroendocrine responses to central blood volume expansion via water immersion blunted in patients with compensated heart failure compared to healthy controls?
Population
19 subjects total: 9 patients with compensated heart failure and 10 age-matched controls.
Comparison
30 minutes of thermoneutral water immersion to… vs Age-matched controls with normal ejection…
Design
Other
Follow-up
30 minutes
Authors
Loading...
May indicate selective reflex impairment in compensated HF; hypothesis-generating for baroreflex heterogeneity and needs prospective validation.
Are cardiovascular and neuroendocrine responses to central blood volume expansion via water immersion blunted in patients with compensated heart failure compared to healthy controls?
In compensated heart failure, reflex control of forearm vascular beds and heart rate is blunted during central blood volume expansion, while baroreflex-mediated systemic vasodilatation and neuroendocrine responses remain preserved.
Gabrielsen et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: