Why the study?
Does haemodialysis with a synthetic polysulphone dialyser compared to a cellulosic cuprophane dialyser prevent acute impairment of endothelial function in chronic haemodialysis patients?
Population
12 chronic haemodialysis patients, mean age 55+/-3 years, time on dialysis 20+/-2 months.
Comparison
Haemodialysis with a synthetic polysulphone… vs Haemodialysis with a cellulosic cuprophane…
Design
RCT, Randomized to HD with either a polysulphone or a cuprophane membrane and…
Follow-up
Immediately before and after haemodialysis
Authors
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Polysulphone dialysers merit preference to avoid acute endothelial dysfunction in haemodialysis; extends membrane-specific vascular protection data.
Does haemodialysis with a synthetic polysulphone dialyser compared to a cellulosic cuprophane dialyser prevent acute impairment of endothelial function in chronic haemodialysis patients?
The use of a synthetic polysulphone dialysis membrane, unlike a cellulosic cuprophane membrane, prevents acute impairment of endothelial function and reduction in serum vitamin E during haemodialysis.
Kosch et al. (2003) studied this question.
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