Key result
Dialysis with polyamide membranes resulted in 14% and 16% lower mean aortic pulse wave velocity at 75 and 135 minutes compared to polysulphone membranes (P<0.05).
Why the study?
Does haemodialysis with polysulphone membranes compared to polyamide membranes acutely increase arterial stiffness in haemodialysis patients?
Population
33 haemodialysis patients (24 in main dialysis group, 9 in blood perfusion without dialysate group)
Comparison
Haemodialysis using polysulphone membranes vs Haemodialysis using polyamide membranes
Design
Cohort
Follow-up
up to 135 minutes during dialysis
Authors
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Polysulphone membranes were associated with higher acute aortic stiffness; leaves open whether membrane choice influences cardiovascular outcomes in haemodialysis.
Does haemodialysis with polysulphone membranes compared to polyamide membranes acutely increase arterial stiffness in haemodialysis patients?
p-value: p=<0.05
Haemodialysis with polysulphone membranes acutely increases aortic stiffness compared to polyamide membranes, potentially due to membrane bioincompatibility.
A. Mourad (2004) studied Haemodialysis patients (n=33). Polyamide membrane vs. Polysulphone membrane was evaluated on Mean aortic (carotid to femoral) pulse wave velocity (PWV) (p=<0.05). Dialysis with polyamide membranes resulted in 14% and 16% lower mean aortic pulse wave velocity at 75 and 135 minutes compared to polysulphone membranes (P<0.05).
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