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April 1, 1996Clinical and Experimental Pharmacology and Physiology

SYMPOSIUM Experimental Biology 1995 Endothelin Receptors: Role in Renal Function and Dysfunction ROLE OF ENDOTHELIN IN RENAL FUNCTION AND DYSFUNCTION

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DBDavid P. BrooksCreighton University

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Implication

Endothelin antagonists may mitigate renal disease progression; leaves open confirmation of clinical efficacy in randomized trials.

Key Points

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Cite This Study

David P. Brooks (1996) studied this question.

synapsesocial.com/papers/6a89ce10b1e5d05ea8ec8778 https://doi.org/10.1111/j.1440-1681.1996.tb02835.x

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.1989 · 418 citations
2Radiocontrast increases plasma and urinary endothelin.1991 · 91 citations
3Reversal of postischemic acute renal failure with a selective endothelinA receptor antagonist in the rat.1994 · 200 citations
4Effects of endothelin receptor antagonist on cyclosporine-induced vasoconstriction in isolated rat renal arterioles.1993 · 223 citations
5Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat1993 · 133 citations