Why the study?
Does arterial blood pH affect lactate uptake by the rabbit hindlimb during hypoxia?
Population
Rabbits (n=10)
Comparison
20 min of arterial hypoxemia with normal pHa vs 20 min of arterial hypoxemia with…
Design
Preclinical
Follow-up
20 min
Authors
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pH may modulate lactate handling in hypoxic muscle; hypothesis-generating for human hypoxemia and should not yet change practice.
Does arterial blood pH affect lactate uptake by the rabbit hindlimb during hypoxia?
During hypoxia, normal arterial pH allows net lactate uptake by resting skeletal muscle, whereas alkalemia results in lactate release.
Gutiérrez et al. (1993) studied this question.
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