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March 21, 2023Journal of the American Heart AssociationOpen Access

Immediately post-TAVI, systolic blood pressure increased (132±21 to 147±23 mm Hg, P<0.001) and cardiac output decreased (4.2±1.5 to 3.9±1.3 L/min, P=0.037), returning to baseline at median 59 days follow-up.

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Why the study?

Various hemodynamic changes occur after TAVI that may impact therapeutic decisions, prompting the use of noninvasive bioimpedance monitoring to evaluate short-term post-TAVI hemodynamics.

Does TAVI alter short-term hemodynamics as measured by noninvasive bioimpedance monitoring in patients with severe aortic stenosis?

Population

97 patients with severe AS undergoing TAVI

Comparison

Post-TAVI, hospital discharge, and follow-up vs baseline pre-TAVI measurements

Design

Prospective observational cohort study

Follow-up

Median 59 days

Authors

TGTzlil GrinbergYAYaron AvivMVMordehay Vaturi

Discussion

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Overview

NICaS may enable noninvasive post-TAVI monitoring; leaves open its clinical utility pending prospective validation.

Structured PICO

Does TAVI alter short-term hemodynamics as measured by noninvasive bioimpedance monitoring in patients with severe aortic stenosis?

P
Population
97 patients with severe aortic stenosis (AS) undergoing TAVI (68% self-expandable, 32% balloon-expandable), 54% women, with multiple comorbidities including hypertension (83%), coronary artery disease (46%), and diabetes (37%).
I
Intervention
Transcatheter aortic valve implantation (TAVI) with noninvasive bioimpedance monitoring (NICaS) at multiple time points (before TAVI, soon after TAVI, at hospital discharge, and during follow-up)
C
Comparator
Baseline (pre-TAVI) measurements
O
Outcome
Short-term hemodynamic changes (systolic blood pressure, total peripheral resistance, cardiac output, stroke volume) measured by NICaSsurrogate

Noninvasive bioimpedance monitoring detects transient but significant hemodynamic changes immediately following TAVI, including increased blood pressure and peripheral resistance with decreased cardiac output, which normalize by 2 months.

Cite This Study

Grinberg et al. (2023) studied this question.

synapsesocial.com/papers/6a89d2e3abe412682d9305a7https://doi.org/10.1161/jaha.122.028479
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Non-Invasive Hemodynamic Monitoring in Transcatheter Aortic Valve Implantation2025
  2. 2Acute Haemodynamic Impact of Transcatheter Aortic Valve Implantation in Patients with Severe Aortic Stenosis2022 · 14 citations
  3. 3Long‐Term Effects of Transcatheter Aortic Valve Implantation on Coronary Hemodynamics in Patients With Concomitant Coronary Artery Disease and Severe Aortic Stenosis2020 · 61 citations
  4. 4Improvement of hemodynamic parameters in aortic stenosis patients with transcatheter valve replacement by using impedance cardiography2022 · 8 citations
  5. 5Acute Hemodynamic Changes Induced by Cardiac Contractility Modulation Evaluated Using the NICaS® System: A Pilot Study2025 · 2 citations