Population
Single permeabilized fibre segments (n = 16) from soleus muscles of rats
Comparison
A single stretch of 40% strain relative to… vs Pre-stretch state (within-fibre comparison)
Design
Preclinical
Authors
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Longest sarcomeres most susceptible to stretch injury in single fibers; leaves open relevance to cardiac muscle in vivo.
In maximally activated single muscle fibres, sarcomeres with the longest lengths prior to stretch are most susceptible to contraction-induced injury.
Macpherson et al. (1997) studied this question.
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