Why the study?
Does RT-PCR improve the detection of Enteroviruses in cerebrospinal fluid compared to cell culture in patients with aseptic meningitis?
Population
68 patients presenting with aseptic meningitis during a summer outbreak in Switzerland
Comparison
Commercially available reverse transcription-PCR… vs Cell culture
Design
Cross-sectional
Authors
Loading...
RT-PCR may improve enterovirus detection in CSF over culture; leaves open prospective validation before routine clinical adoption.
Does RT-PCR improve the detection of Enteroviruses in cerebrospinal fluid compared to cell culture in patients with aseptic meningitis?
Commercial RT-PCR assay provides a rapid and highly sensitive diagnosis of enteroviral meningitis compared to standard cell culture, potentially influencing clinical decisions.
Gorgievski-Hrisoho et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: