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May 1, 2000The Journal of Infectious DiseasesOpen Access

Human Caliciviruses in Acute Gastroenteritis of Young Children in the Community

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Why the study?

What is the prevalence of human caliciviruses compared to other viruses in acute gastroenteritis episodes among young children?

Population

Prospectively followed children between 2 months and 2 years of age with episodes of acute gastroenteritis…

Design

Cohort

Authors

SHShinjiro HonmaNational Institutes of HealthSNShuji NakataSapporo Medical UniversityTVTimo VesikariBen-Gurion University of the Negev

Discussion

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Implication

Supports considering caliciviruses in pediatric gastroenteritis diagnostics; leaves open prospective studies on severity and prevention.

Structured PICO

What is the prevalence of human caliciviruses compared to other viruses in acute gastroenteritis episodes among young children?

P
Population
Prospectively followed children between 2 months and 2 years of age with episodes of acute gastroenteritis in Finland (832 episodes).
I
Intervention
PCR and reverse transcription (RT)-PCR assays for detecting rotaviruses, enteric adenoviruses, astroviruses, and human caliciviruses (NLVs and SLVs).
O
Outcome
Detection rate of viruses in acute gastroenteritis episodes.

Human caliciviruses are as common as rotaviruses in causing acute gastroenteritis in children under 2 years of age, with NLVs causing more severe disease than SLVs.

Cite This Study

Honma et al. (2000) studied this question.

synapsesocial.com/papers/6a8a50ce788d49930fcbf981https://doi.org/10.1086/315590
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Also Consider

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  1. 1Correlation of patient immune responses with genetically characterized small round-structured viruses involved in outbreaks of nonbacterial acute gastroenteritis in the United States, 1990 to 19951997 · 180 citations
  2. 2Adenovirus types 40 and 41 and rotaviruses associated with diarrhea in children from Guatemala1990 · 99 citations
  3. 3Improved detection of rotavirus shedding by polymerase chain reaction1991 · 100 citations
  4. 4Astrovirus as a cause of gastroenteritis in Japan1994 · 52 citations
  5. 5Polymerase chain reaction detection of small round‐structured viruses from two related hospital outbreaks of gastroenteritis using inosine‐containing primers1995 · 84 citations