Population
275 samples of human γ-globulin tested in Rhesus kidney or HEp-2 cell cultures
Comparison
Globulins prepared from placental extracts vs Globulins prepared from venous blood and a…
Design
Preclinical
Authors
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Variability in gamma-globulin potency requires standardization; animal data leaves open clinical translation and optimal sourcing.
The study demonstrates significant variability in poliovirus antibody content among human gamma-globulin preparations, highlighting the need for careful standardization.
Uhlendorf et al. (1964) studied this question.
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