Why the study?
Hypotension after spinal anesthesia during cesarean section can harm the parturient and fetus, and ketamine's cardiovascular-stimulating effects may prevent this.
Does prophylactic intravenous ketamine prevent intraoperative hypotension in term pregnant women undergoing elective cesarean section under spinal anesthesia?
Population
98 American Society of Anesthesiologists term pregnant women undergoing elective cesarean section under spinal anesthesia
Comparison
Prophylactic intravenous ketamine 15 mg vs normal saline bolus
Design
Double-blinded randomized controlled study
Follow-up
Till the end of the operation
Authors
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Prophylactic low-dose ketamine was associated with fewer hypotensive episodes in cesarean delivery; leaves open confirmation in larger trials before practice change.
Does prophylactic intravenous ketamine prevent intraoperative hypotension in term pregnant women undergoing elective cesarean section under spinal anesthesia?
Prophylactic low-dose intravenous ketamine significantly reduces the incidence of intraoperative hypotension and the need for ephedrine in parturients undergoing cesarean section under spinal anesthesia.
BP et al. (2023) studied this question.
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