Why the study?
Does early multiple sclerosis alter the Lyapunov exponent of heart rate dynamics compared to healthy controls?
Population
22 participants: 11 young patients with relapsing remitting definite multiple sclerosis in relapse-free and…
Comparison
Measurement of heart rate dynamics under… vs Healthy controls
Design
Case-control
Authors
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Early MS may alter heart rate dynamics; leaves open whether Lyapunov exponents aid autonomic risk stratification.
Does early multiple sclerosis alter the Lyapunov exponent of heart rate dynamics compared to healthy controls?
Early multiple sclerosis is associated with lower Lyapunov exponents of heart rate dynamics, suggesting altered central-autonomic organization.
Ganz et al. (1993) studied this question.
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