Population
Rat hippocampus (for cloning) and Xenopus oocytes (for functional expression)
Design
Preclinical
Authors
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Hypothesis-generating in animal models; leaves open clinical relevance of Kv4.3 in human CNS excitability disorders.
The cloning and mapping of Kv4.3 demonstrate its widespread distribution in the CNS and its function as an A-type potassium channel regulating neuronal excitability.
Tsaur et al. (1997) studied this question.
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