June 28, 2017JAMA Cardiology
Health Status Benefits of Transcatheter vs Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis at Intermediate Surgical Risk
Why the study?
Does transcatheter aortic valve replacement improve health status compared to surgical aortic valve replacement in intermediate-risk patients with severe aortic stenosis?
Population
2032 intermediate-risk patients with severe aortic stenosis (AS), mean age 81.4, 54.9% male.
Comparison
Transcatheter aortic valve replacement with the… vs Surgical aortic valve replacement (SAVR)
Design
RCT, randomized
Follow-up
2 years
Authors
Discussion
Loading...
Member takes
Implication
Provides a faster early recovery for intermediate-risk patients; confirms the short-term quality-of-.
Structured PICO
Does transcatheter aortic valve replacement improve health status compared to surgical aortic valve replacement in intermediate-risk patients with severe aortic stenosis?
P
Population
2032 intermediate-risk patients with severe aortic stenosis (AS), mean age 81.4, 54.9% male.
I
Intervention
Transcatheter aortic valve replacement (TAVR) with the Sapien XT valve
C
Comparator
Surgical aortic valve replacement (SAVR)
O
Outcome
Health status assessed at baseline, 1 month, 1 year, and 2 years using the Kansas City Cardiomyopathy Questionnaire (KCCQ), Medical Outcomes Study Short Form-36 (SF-36), and EuroQOL-5Dpatient reported
TAVR provides early health status benefits compared to SAVR at 1 month in intermediate-risk patients with severe aortic stenosis when performed via transfemoral access, but both procedures yield similar improvements at 1 and 2 years.
Limitations
- Longer term follow-up is needed to assess the durability of quality-of-life improvement with TAVR vs SAVR in this population.
Cite This Study
Baron et al. (2017) studied this question.