October 4, 2011Circulation
Health-Related Quality of Life After Transcatheter Aortic Valve Replacement in Inoperable Patients With Severe Aortic Stenosis
Why the study?
Does transcatheter aortic valve replacement improve health-related quality of life compared to standard therapy in inoperable patients with severe aortic stenosis?
Population
358 patients with symptomatic, severe aortic stenosis who were not candidates for surgical valve replacement
Comparison
Transcatheter aortic valve replacement (TAVR) vs Standard therapy
Design
RCT, randomized
Follow-up
12 months
Authors
Discussion
Loading...
Member takes
Overview
Supports TAVR for inoperable severe aortic stenosis; extends survival data with patient-reported outcomes.
Structured PICO
Does transcatheter aortic valve replacement improve health-related quality of life compared to standard therapy in inoperable patients with severe aortic stenosis?
P
Population
358 patients with symptomatic, severe aortic stenosis who were not candidates for surgical valve replacement (inoperable)
I
Intervention
Transcatheter aortic valve replacement (TAVR)
C
Comparator
Standard therapy
O
Outcome
Kansas City Cardiomyopathy Questionnaire (KCCQ) overall summary scorepatient reported
In inoperable patients with severe aortic stenosis, TAVR significantly improves health-related quality of life compared to standard therapy at 1 year.
Cite This Study
Reynolds et al. (2011) studied this question.