Why the study?
Does intrapericardial administration of adenovirus result in effective gene transfer to the pericardium and myocardium in dogs?
Does intrapericardial administration of adenovirus result in effective gene transfer to the pericardium and myocardium in dogs?
Intrapericardial administration of adenovirus provides an effective method for gene transfer to the visceral and parietal pericardium in a canine model.
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Provides proof-of-concept for pericardial gene delivery in dogs; leaves open translation to human cardiac applications.
Lamping et al. (1997) studied this question.
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