What question did this study set out to answer?

To evaluate the epidemiology, clinical presentation, radiographic findings, and outcomes of lower respiratory tract infections caused by different adenovirus serotypes in hospitalized children.

May 15, 2001Clinical Infectious Diseases

Lower Respiratory Tract Infections due to Adenovirus in Hospitalized Korean Children: Epidemiology, Clinical Features, and Prognosis

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Authors

JHJimin Hong HLHyo‐Jeong Lee PPPedro A. Piedra

Discussion

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Overview

Retrospective study observes high mortality and lung damage from adenovirus serotypes 3 and 7 in young children, highlighting the severe risk of epidemic viral strains.

Key Points

To evaluate the epidemiology, clinical presentation, radiographic findings, and outcomes of lower respiratory tract infections caused by different adenovirus serotypes in hospitalized children.
Reviewed all medical records and viral cultures of children hospitalized with lower respiratory tract infections (LRTIs) at Seoul National University Children's Hospital between 1990 and 1998 (N=1,472).
Isolated adenovirus from nasal aspirate specimens, determined viral serotypes, and evaluated clinical course, radiographic features, and mortality.
Adenovirus was recovered from 87 of 1,472 children (5.9%) with LRTI, occurring predominantly in children younger than 2 years (71%) and younger than 5 years (94%).
Serotype 7 was the most frequent (41% [36/87]), followed by serotype 2 (15% [13/87]) and serotype 3 (15% [13/87]); serotypes 3 and 7 occurred in epidemics and featured frequent extrapulmonary abnormalities, homogeneous consolidation, and pleural effusion.
Overall mortality was 12%, reaching 19% among children infected with serotype 7; residual sequelae occurred in 50% (6/12) of patients with serotype 3 and in 25% (9/36) of patients with serotype 7.

Cite This Study

Hong et al. (2001) studied this question.

synapsesocial.com/papers/6a8a6f8d788d49930fcbfe83 https://doi.org/10.1086/320146

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May 15, 2001Clinical Infectious Diseases

Lower Respiratory Tract Infections due to Adenovirus in Hospitalized Korean Children: Epidemiology, Clinical Features, and Prognosis

View Full Paper

Ask AI

Bookmark

Authors

JHJimin Hong HLHyo‐Jeong Lee PPPedro A. Piedra

Discussion

Member takes

Overview

Retrospective study observes high mortality and lung damage from adenovirus serotypes 3 and 7 in young children, highlighting the severe risk of epidemic viral strains.

Key Points

To evaluate the epidemiology, clinical presentation, radiographic findings, and outcomes of lower respiratory tract infections caused by different adenovirus serotypes in hospitalized children.
Reviewed all medical records and viral cultures of children hospitalized with lower respiratory tract infections (LRTIs) at Seoul National University Children's Hospital between 1990 and 1998 (N=1,472).
Isolated adenovirus from nasal aspirate specimens, determined viral serotypes, and evaluated clinical course, radiographic features, and mortality.
Adenovirus was recovered from 87 of 1,472 children (5.9%) with LRTI, occurring predominantly in children younger than 2 years (71%) and younger than 5 years (94%).
Serotype 7 was the most frequent (41% [36/87]), followed by serotype 2 (15% [13/87]) and serotype 3 (15% [13/87]); serotypes 3 and 7 occurred in epidemics and featured frequent extrapulmonary abnormalities, homogeneous consolidation, and pleural effusion.
Overall mortality was 12%, reaching 19% among children infected with serotype 7; residual sequelae occurred in 50% (6/12) of patients with serotype 3 and in 25% (9/36) of patients with serotype 7.

Cite This Study

Hong et al. (2001) studied this question.

synapsesocial.com/papers/6a8a6f8d788d49930fcbfe83 https://doi.org/10.1086/320146

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