Population
Lentiviral vectors and nondividing cells
Comparison
Multigene lentiviral vectors using HIV-1… vs Lentivirus vectors expressing wild-type tat or…
Design
Preclinical
Authors
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Preclinical support for multigene lentiviral vectors without titer loss; leaves open translation to human cardiovascular gene therapy.
Multigene lentiviral vectors using splicing signals or IRES can successfully express multiple genes without compromising viral titer or infectivity in nondividing cells.
Zhu et al. (2001) studied this question.
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